The runway number typically changes on the 5 degrees mark instead on on the 0 degree mark. So runway 15 can have a magnetic heading of 145 degrees to 154.9 degrees
There are airports like KTUS that have a 11/29 runway assignment but the magnetic course is 123.4 degrees. The reason this is because of the closeness of Davis Monthan AFB (DMA). The runways at both airports are exactly parallel. To avoid an aircraft landing on the wrong airport / runway; ATC determined to move one airports runway to a different number.